diff --git a/RFM69.cpp b/RFM69.cpp
index aac4530..8e18045 100644
--- a/RFM69.cpp
+++ b/RFM69.cpp
@@ -37,8 +37,10 @@ uint8_t RFM69::ACK_REQUESTED;
 uint8_t RFM69::ACK_RECEIVED; // should be polled immediately after sending a packet with ACK request
 int16_t RFM69::RSSI;          // most accurate RSSI during reception (closest to the reception)
 volatile bool RFM69::_haveData;
+RFM69 *RFM69::_instance = nullptr;
 
 RFM69::RFM69(uint8_t slaveSelectPin, uint8_t interruptPin, bool isRFM69HW_HCW, SPIClass *spi) {
+  _instance = this;
   _slaveSelectPin = slaveSelectPin;
   _interruptPin = interruptPin;
   _mode = RF69_MODE_STANDBY;
@@ -152,6 +154,11 @@ bool RFM69::initialize(uint8_t freqBand, uint16_t nodeID, uint8_t networkID)
   return true;
 }
 
+void RFM69::setIsrCallback(void (*callback)())
+{
+  _isrCallback = callback;
+}
+
 // return the frequency (in Hz)
 uint32_t RFM69::getFrequency()
 {
@@ -446,7 +453,11 @@ void RFM69::interruptHandler() {
 }
 
 // internal function
-ISR_PREFIX void RFM69::isr0() { _haveData = true; }
+ISR_PREFIX void RFM69::isr0() {
+  _haveData = true;
+  if (_instance->_isrCallback)
+    _instance->_isrCallback();
+}
 
 // internal function
 void RFM69::receiveBegin() {
diff --git a/RFM69.h b/RFM69.h
index 491fa7e..2d511e2 100644
--- a/RFM69.h
+++ b/RFM69.h
@@ -201,6 +201,7 @@ class RFM69 {
     RFM69(uint8_t slaveSelectPin=RF69_SPI_CS, uint8_t interruptPin=RF69_IRQ_PIN, bool isRFM69HW_HCW=false, SPIClass *spi=nullptr);
 
     bool initialize(uint8_t freqBand, uint16_t ID, uint8_t networkID=1);
+    void setIsrCallback(void (*callback)());
     void setAddress(uint16_t addr);
     void setNetwork(uint8_t networkID);
     virtual bool canSend();
@@ -247,6 +248,8 @@ class RFM69 {
     void interruptHandler();
     virtual void interruptHook(uint8_t CTLbyte __attribute__((unused))) {};
     static volatile bool _haveData;
+    static RFM69 *_instance;
+    void (*_isrCallback)() = nullptr;
     virtual void sendFrame(uint16_t toAddress, const void* buffer, uint8_t size, bool requestACK=false, bool sendACK=false);
 
     // for ListenMode sleep/timer